English version Version Française
 About CNRS Life Sciences Other CNRS web sites
 
 

Director:
Deputy director:

The Institute of Human Genetics (Institut de Génétique Humaine, IGH) is a major CNRS unit dedicated to excellence in fundamental research and pathology. The principal research interests of the IGH are genome dynamics, developmental genetics, epigenetics, and molecular and cellular pathology.


Laboratory's News

 


8th IGH Seminar Series on Genetics and Development

Genopolys or IGH, at 11:30, from March 6th, 2015 to July 3rd, 2015








Seminars of the month @ IGH


  • 03-07-2015 (11h30) "Seminar series on Genetics & Development : Multiple roles of PP6 phosphatase in cellular signaling"
    David BRAUTIGAN (University of Virginia School of Medicine, Charlottesville, USA)
  • 03-07-2015 (14h00) "LINE-1 retrotransposition in Fanconi Anemia patients"
    Jose Luis GARCIA-PEREZ (Biology of LINE-1 retroelements - Dept of Human DNA Variability - GENYO (Center for Genomics and Oncological Research)-University of Granada -Spain)
  • 03-07-2015 (14h00) "Interview post-doc - Unraveling transcriptome complexity in plants: The alternative splicing landscape of Arabidopsis thaliana"
    Yamile Maquez (Barta's lab Max F Perutz Laboratories Vienna, Austria)


Some recent papers


  • Gonzalez I, Munita R, Agirre E, Dittmer TA, Gysling K, Misteli T, Luco RF. "A lncRNA regulates alternative splicing via establishment of a splicing-specific chromatin signature" (2015), Nat Struct Mol Biol: 22, 5, 370-376 PubMed
  • Fragkos M, Ganier O, Coulombe P, Méchali M "DNA replication origin activation in space and time" (2015), Nat Rev Mol Cell Biol: 16(6):360-74 PubMed
  • Ide, S., Dejardin, J. "End-targeting proteomics of isolated chromatin segments of a mammalian ribosomal RNA gene promoter" (2015), Nat. Commun.: 6, 6674 PubMed
  • Borde V, de Massy B "Meiosis: early DNA double-strand breaks pave the way for inter-homolog repair" (2015), Dev Cell: 32(6):663-4 PubMed
  • Sexton, T., Cavalli, G. "The Role of Chromosome Domains in Shaping the Functional Genome" (2015), CELL: 160, 6, 1049–1059 PubMed
  • Marzec, P., Armenise, C., Perot, G., Roumelioti, F.M., Basyuk, E., Gagos, S., Chibon, F., Dejardin, J. "Nuclear-Receptor-Mediated Telomere Insertion Leads to Genome Instability in ALT Cancer" (2015), CELL: 160, 5, 913-927 PubMed
  • Saksouk N, Barth TK, Ziegler-Birling C, Olova N, Nowak A, Rey E, Mateos-Langerak J, Urbach S, Reik W, Torres-Padilla ME, Imhof A, Déjardin J. "Redundant Mechanisms to Form Silent Chromatin at Pericentromeric Regions Rely on BEND3 and DNA Methylation" (2014), Mol Cell: 56(4):580-94 PubMed
  • Stadelmayer B, Micas G, Gamot A, Martin P, Malirat N, Koval S, Raffel R, Sobhian B, Severac D, Rialle S, Parrinello H, Cuvier O, Benkirane M "Integrator complex regulates NELF-mediated RNA polymerase II pause/release and processivity at coding genes" (2014), Nat Commun: 5:5531 PubMed
  • de Massy B. "Human genetics. Hidden features of human hotspots" (2014), Science: 346(6211):808-9 PubMed
  • Cole F, Baudat F, Grey C, Keeney S, de Massy B, Jasin M. "Mouse tetrad analysis provides insights into recombination mechanisms and hotspot evolutionary dynamics" (2014), Nat Genet.: 46, 10, 1072-1080 PubMed
  • Yoshida K, Bacal J, Desmarais D, Padioleau I, Tsaponina O, Chabes A, Pantesco V, Dubois E, Parrinello H, Skrzypczak M, Ginalski K, Lengronne A, Pasero P "The histone deacetylases sir2 and rpd3 act on ribosomal DNA to control the replication program in budding yeast." (2014), Mol Cell.: 54(4):691-697 PubMed
  • Gonzalez I, Mateos-Langerak J, Thomas A, Cheutin T, Cavalli G. "Identification of Regulators of the Three-Dimensional Polycomb Organization by a Microscopy-Based Genome-wide RNAi Screen" (2014), Mol Cell: 54(3):485-99 PubMed
  • Moran, Y., Fredman, D., Praher, D., Li Z. L., Meng Wee,L., Rentzsch, F., Zamore,P.D., Technau, U., Seitz H. "Cnidarian microRNAs frequently regulate targets by cleavage" (2014), Genome Research: 24(4):651-63 PubMed
  • Laguette,N., Bregnard, C., Hue, P., Basbous, J., Yatim, A., Larroque, M., Kirchhoff, F., Constantinou, A., Sobhian, B., Benkirane, M. "Premature Activation of the SLX4 Complex by Vpr Promotes G2/M Arrest and Escape from Innate Immune Sensing" (2014), CELL: 156, 1-2, 134-145 PubMed
  • Van der Laan, S., Crozet, C., Tsanov, N., and Maiorano, D "High Dub3 expression in mouse ESC couples the G1/S checkpoint to pluripotency" (2013), Molecular Cell: 52, 3, 366-379 PubMed
  • Bétous R., Pillaire, M-J, Pierini, L., Van der Laan, S., Recolin B., Ohl-Séguy, E., Guo, C., Niimi, N., Gruz, P., Nohmi, T. Friedberg, E., Cazaux, C., Maiorano, D* and Hoffmann J-S*. * corresponding authors "DNA polymerase k-dependent DNA synthesis at stalled replication forks is important for Chk1 activation" (2013), EMBO Journal: 32(15):2172-85 PubMed
  • Lossaint G, Larroque M, Ribeyre C, Bec N, Larroque C, Décaillet C, Gari K, Constantinou A. "FANCD2 Binds MCM Proteins and Controls Replisome Function upon Activation of S Phase Checkpoint Signaling." (2013), Mol Cell.: 51(5):678-690 PubMed
  • Iovino N, Ciabrelli F, Cavalli G. "PRC2 Controls Drosophila Oocyte Cell Fate by Repressing Cell Cycle Genes." (2013), Dev Cell: 26(4):431-9 PubMed
  • Berkhout B, Lever A, Wainberg M, Fassati A, Borrow P, Fujii M "Monsef Benkirane awarded 2013 Ming K. Jeang Foundation Retrovirology Prize: Landmark HIV-1 research honoured" (2013), Retrovirology: 10, 1, 28 PubMed
  • Cavalli, G., Mistelli, T. "Functional implications of genome topology" (2013), Nat. Struct. Mol. Biol: 20, 3, 290-299 PubMed

Last minute IGH NEWS

Today 04-07-2015

2014

Opportunities1 job / training period opportunities

 

All NewsNews / Archives


iGHazette - Staff only

Don't missNext seminars & congresses

----- @Int'l

Web Site 26th Ion Channel Meeting
13-09-2015, Sète, France

Web Site ICTE2016: International Congress on Transposable Elements
16-04-2016, Saint-Malo, France

Web Site 29th French Drosophila Conference
13-10-2015, La Grande-Motte, France

IGH papers 1462 Publications

... the 2 last ones

Tarver JE, Cormier A, Pinzón N, Taylor RS, Carré W, Strittmatter M, Seitz H, Coelho SM, Cock JM. microRNAs and the evolution of complex multicellularity: identification of a large, diverse complement of microRNAs in the brown alga Ectocarpus (2015), Nucleic Acids Res.
Vlachakis D, Fakourelis P, Megalooikonomou V, Makris C, Kossida S. DrugOn: a fully integrated pharmacophore modeling and structure optimization toolkit (2015), PeerJ.

Home pageSmart printContactCoordinatesCopyrightsPersonnal AccessWebmail  Mailing Lists

 

 

CNRS
Institute of Human Genetics
  

Directories

Search

the Institute Servers



the CNRS WEB



  INSTITUTE of HUMAN GENETICS
  CNRS UPR 1142
  Montpellier, France