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The Institute of Human Genetics (Institut de Génétique Humaine, IGH) is a major CNRS unit dedicated to excellence in fundamental research and pathology. The principal research interests of the IGH are genome dynamics, developmental genetics, epigenetics, and molecular and cellular pathology.


Laboratory's News

 


8th IGH Seminar Series on Genetics and Development

Genopolys or IGH, at 11:30, from March 6th, 2015 to July 3rd, 2015







Seminar Series on Genome Dynamics 2014-2015

Amphitheater Genopolys, at 11:30, from October 6th to April 3rd







Seminars of the month @ IGH


  • 06-03-2015 (11h30) "Seminar series on Genetics & Development : Small RNA Biology of Germ Cells"
    René KETTING (Institute of Molecular Biology, Mainz, Germany)
  • 13-03-2015 (11h30) "Seminar series on Genetics & Development :Nutrients, growth and survival"
    Marci MILAN
  • 16-03-2015 (11h30) "Chromatin dynamics in proliferating and senescent cells"
    Armelle Corpet
  • 20-03-2015 (11h30) "Seminar series on Genetics & Development : Genome Biology of redundant Drosophila Sox proteins"
    Steve RUSSEL (Department of Genetics & Cambridge Systems Biology Centre, Cambridge, UK)
  • 27-03-2015 (11h30) "Seminar series on Genome Dynamics: Chromosome Dynamics from Bacteria to Mammalian Cells"
    Nancy KLECKNER (Harvard University, Molecular & Cellular Biology, Cambridge, USA)


Some recent papers


  • Marzec, P., Armenise, C., Perot, G., Roumelioti, F.M., Bauyk, E., Gagos, S., Chibon, F., Dejardin, J. "Nuclear-Receptor-Mediated Telomere Insertion Leads to Genome Instability in ALT Cancer" (2015), CELL: 160, 5, 913-927
  • Saksouk N, Barth TK, Ziegler-Birling C, Olova N, Nowak A, Rey E, Mateos-Langerak J, Urbach S, Reik W, Torres-Padilla ME, Imhof A, Déjardin J. "Redundant Mechanisms to Form Silent Chromatin at Pericentromeric Regions Rely on BEND3 and DNA Methylation" (2014), Mol Cell: 56(4):580-94 PubMed
  • Stadelmayer B, Micas G, Gamot A, Martin P, Malirat N, Koval S, Raffel R, Sobhian B, Severac D, Rialle S, Parrinello H, Cuvier O, Benkirane M "Integrator complex regulates NELF-mediated RNA polymerase II pause/release and processivity at coding genes" (2014), Nat Commun: 5:5531 PubMed
  • de Massy B. "Human genetics. Hidden features of human hotspots" (2014), Science: 346(6211):808-9 PubMed
  • Cole F, Baudat F, Grey C, Keeney S, de Massy B, Jasin M. "Mouse tetrad analysis provides insights into recombination mechanisms and hotspot evolutionary dynamics" (2014), Nat Genet.: 46, 10, 1072-1080 PubMed
  • Yoshida K, Bacal J, Desmarais D, Padioleau I, Tsaponina O, Chabes A, Pantesco V, Dubois E, Parrinello H, Skrzypczak M, Ginalski K, Lengronne A, Pasero P "The histone deacetylases sir2 and rpd3 act on ribosomal DNA to control the replication program in budding yeast." (2014), Mol Cell.: 54(4):691-697 PubMed
  • Gonzalez I, Mateos-Langerak J, Thomas A, Cheutin T, Cavalli G. "Identification of Regulators of the Three-Dimensional Polycomb Organization by a Microscopy-Based Genome-wide RNAi Screen" (2014), Mol Cell: 54(3):485-99 PubMed
  • Moran, Y., Fredman, D., Praher, D., Li Z. L., Meng Wee,L., Rentzsch, F., Zamore,P.D., Technau, U., Seitz H. "Cnidarian microRNAs frequently regulate targets by cleavage" (2014), Genome Research: 24(4):651-63 PubMed
  • Laguette,N., Bregnard, C., Hue, P., Basbous, J., Yatim, A., Larroque, M., Kirchhoff, F., Constantinou, A., Sobhian, B., Benkirane, M. "Premature Activation of the SLX4 Complex by Vpr Promotes G2/M Arrest and Escape from Innate Immune Sensing" (2014), CELL: 156, 1-2, 134-145 PubMed
  • Van der Laan, S., Crozet, C., Tsanov, N., and Maiorano, D "High Dub3 expression in mouse ESC couples the G1/S checkpoint to pluripotency" (2013), Molecular Cell: 52, 3, 366-379 PubMed
  • Bétous R., Pillaire, M-J, Pierini, L., Van der Laan, S., Recolin B., Ohl-Séguy, E., Guo, C., Niimi, N., Gruz, P., Nohmi, T. Friedberg, E., Cazaux, C., Maiorano, D* and Hoffmann J-S*. * corresponding authors "DNA polymerase k-dependent DNA synthesis at stalled replication forks is important for Chk1 activation" (2013), EMBO Journal: 32(15):2172-85 PubMed
  • Lossaint G, Larroque M, Ribeyre C, Bec N, Larroque C, Décaillet C, Gari K, Constantinou A. "FANCD2 Binds MCM Proteins and Controls Replisome Function upon Activation of S Phase Checkpoint Signaling." (2013), Mol Cell.: 51(5):678-690 PubMed
  • Iovino N, Ciabrelli F, Cavalli G. "PRC2 Controls Drosophila Oocyte Cell Fate by Repressing Cell Cycle Genes." (2013), Dev Cell: 26(4):431-9 PubMed
  • Berkhout B, Lever A, Wainberg M, Fassati A, Borrow P, Fujii M "Monsef Benkirane awarded 2013 Ming K. Jeang Foundation Retrovirology Prize: Landmark HIV-1 research honoured" (2013), Retrovirology: 10, 1, 28 PubMed
  • Cavalli, G., Mistelli, T. "Functional implications of genome topology" (2013), Nat. Struct. Mol. Biol: 20, 3, 290-299 PubMed

Last minute IGH NEWS

Today 01-03-2015

2013

Opportunities4 job / training period opportunities

 

All NewsNews / Archives


iGHazette - Staff only

Don't missNext seminars & congresses

----- @IGH

Seminar series on Genome Dynamics: Stress, transposons and evolution
03-04-2015, Sergio PIMPINELLI (Dipartimento di Genetica e Biologia Molecolare, Università di Roma «La Sapienza» Roma, Italy)

Seminar series on Genetics & Development : Transcriptomic chronology of skeletal muscle stem cells identifies SoxF genes as novel regulators of satellite cell renewal
24-04-2015, Frédéric RELAIX (Faculté de Médecine U 955, Créteil, France)

Seminar series on Genetics & Development : A memory found?
30-04-2015, Scott WADDELL (- Centre for Neural Circuits & Behaviour, OXFORD, UK)

An evolutionary perspective on human germline mutation
26-06-2015, Molly PRZEWORSKI (Biological Science, Columbia University, USA)

Seminar series on Genetics & Development : Regulation of E-cadherin and epithelial-mesenchymal plasticity by Protein Phosphatase-6
03-07-2015, David BRAUTIGAN (University if Virginia School of Medicine, Charlottesville, USA)

----- @Int'l

Web Site Chromatin Meets South 2015
04-06-2015, Marseille, Fr.

IGH papers 1439 Publications

... the 2 last ones

Marzec, P., Armenise, C., Perot, G., Roumelioti, F.M., Bauyk, E., Gagos, S., Chibon, F., Dejardin, J.. Nuclear-Receptor-Mediated Telomere Insertion Leads to Genome Instability in ALT Cancer (2015), CELL.
Baliakas P, Agathangelidis A, Hadzidimitriou A, Sutton LA, Minga E, Tsanousa A, Scarfò L, Davis Z, Yan XJ, Shanafelt T, Plevova K, Sandberg Y, Vojdeman FJ, Boudjogra M, Tzenou T, Chatzouli M, Chu CC, Veronese S, Gardiner A, Mansouri L, Smedby KE, Pedersen LB, Moreno D, Van Lom K, Giudicelli V, Francova HS, Nguyen-Khac F, Panagiotidis P, Juliusson G, Angelis L, Anagnostopoulos A, Lefranc MP, Facco M, Trentin L, Catherwood M, Montillo M, Geisler CH, Langerak AW, Pospisilova S, Chiorazzi N, Oscier D, Jelinek DF, Darzentas N, Belessi C, Davi F, Ghia P, Rosenquist R, Stamatopoulos K. Not all IGHV3-21 chronic lymphocytic leukemias are equal: prognostic considerations (2015), Blood.

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  INSTITUTE of HUMAN GENETICS
  CNRS UPR 1142
  Montpellier, France