• 110 / 117
    Parity men / women

  • 9
    ERC Laureates

  • 3
    Departments

  • 92
    PhD Theses and HDR defences

  • 22
    Research teams

  • 1731
    Publications

The IGH is dedicated to excellence in fundamental research and pathology. The principal research interests of the IGH are genome dynamics, developmental genetics, epigenetics, and molecular and cellular pathology.

Events

  • 2nd IGH PhD students and Postdocs Meeting (IP2M), “The life of cancer cells”, taking place in Montpellier, France, on the 12th and 13th of December of 2019.

    12 Dec - 13 Dec 2019 / 13:00
    Amphithéâtre Genopolys

  • MiniSymposium: Cellular compartmentalization and protein phase separation

    21 Nov - 22 Nov 2019 / 09:00
    Amphithéâtre Genopolys

  • Ecole Thématique InteRNAt - petits ARN régulateurs eucaryotiques (microARN, siARN et piARN)

    06 Oct - 10 Oct 2019 / 08:00
    Sète - Le LAZARET

  • SOX Meeting 2019 : Vth International SOX Research Conference

    29 Sep - 03 Oct 2019 / 08:00
    Domaine de Mousquety 84800 L'Isle-sur-la-Sorgue

  • Genome integrity - A lifetime's challenge

    22 Nov - 23 Nov 2018
    Amphithéatre Genopolys - Campus Arnaud de Villeneuve, Montpellier

  • IGH | Mini Symposium

    09 Nov 2018 / 08:00
    Amphithéâtre Genopolys

Papers

  • Advances in epigenetics link genetics to the environment and disease

    Giacomo Cavalli and Edith Heard

    2019 - Nature, 10.1038/s41586-019-1411-0

  • Involvement of G-quadruplex regions in mammalian replication origin activity

    Prorok P., Artufel, M., Aze, A., Coulombe, P., Peifer I., Lacroix L., Guédin A., Mergny J.L., Damas...

    2019 - Nature Com.

  • Mouse ANKRD31 Regulates Spatiotemporal Patterning of Meiotic Recombination Initiation and Ensures Re...

    Papanikos F, Clément JAJ, Testa E, Ravindranathan R, Grey C, Dereli I, Bondarieva A, Valerio-Cabrer...

    2019 - Mol Cell

    31000436

  • OBI1, an ORC ubiquitin ligase promoting DNA replication origin firing

    Coulombe P, Nassar J, Peiffer I, Stanojcic S, Sterkers Y, Delamarre A, Bocquet S. and Méchali M.

    2019 - Nature Com.

  • SAMHD1 acts at stalled replication forks to prevent interferon induction.

    Coquel F, Silva MJ, Técher H, Zadorozhny K, Sharma S, Nieminuszczy J, Mettling C, Dardillac E, Bart...

    2018 - Nature, 557(7703):57-61

    29670289

  • Overexpression of Claspin and Timeless protects cancer cells from replication stress in a checkpoint...

    Bianco JN, Bergoglio V, Lin YL, Pillaire MJ, Schmitz AL, Gilhodes J, Lusque A, Mazières J, Lacroix-...

    2019 - Nat Commun, 10(1):910

    30796221

  • Functional lability of RNA-dependent RNA polymerases in animals.

    Pinzón N, Bertrand S, Subirana L, Busseau I, Escrivá H, Seitz H

    2019 - PLoS Genet, 15(2):e1007915

    30779744

  • Amphioxus functional genomics and the origins of vertebrate gene regulation.

    Marlétaz F, Firbas PN, Maeso I, Tena JJ, Bogdanovic O, Perry M, Wyatt CDR, de la Calle-Mustienes E,...

    2018 - Nature

    30464347

  • Challenges and guidelines toward 4D nucleome data and model standards.

    Marti-Renom MA, Almouzni G, Bickmore WA, Bystricky K, Cavalli G, Fraser P, Gasser SM, Giorgetti L, H...

    2018 - Nat Genet, 50(10):1352-1358

    30262815

  • Sex reversal following deletion of a single distal enhancer of Sox9.

    Gonen N, Futtner CR, Wood S, Garcia-Moreno SA, Salamone IM, Samson SC, Sekido R, Poulat F, Maatouk D...

    2018 - Science, 360(6396):1469-1473

    29903884

  • Loss of PRC1 induces higher-order opening of Hox loci independently of transcription during Drosophi...

    Cheutin T, Cavalli G

    2018 - Nat Commun, 9(1):3898

    30254245

  • FTSJ3 is an RNA 2'-O-methyltransferase recruited by HIV to avoid innate immune sensing.

    Ringeard M, Marchand V, Decroly E, Motorin Y, Bennasser Y

    2019 - Nature

    30626973