Coming soon at IGH
RNA-mediated genome instability
Given by Andres AGUILERA
Amphithéâtre Genopolys
Fri. 23 October 2020 - 11:30
The Institute of Human Genetics is working at the forefront of the scientific response to COVID-19
During the developing COVID-19 pandemic the Institute of Human Genetics and its researchers are playing their part in tackling the virus.
The IGH is dedicated to excellence in fundamental research and pathology. The principal research interests of the IGH are genome dynamics, developmental genetics, epigenetics, and molecular and cellular pathology.
Upcoming
23 October 2020 - 11:30
/ Amphithéâtre Genopolys
Papers
Tubulin modifying enzymes as target for the treatment of tau-related diseases
Krzysztof Rogowski, Khaled Hached, Carole Crozet, Siem Van Der Laan
2020 - Pharmacology & Therapeutics
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Functions of PIWI Proteins in Gene Regulation: New Arrows Added to the piRNA Quiver
Anne Ramat, Martine Simonelig
2020 - Trends in Genetics
The Mi-2 nucleosome remodeler and the Rpd3 histone deacetylase are involved in piRNA-guided heteroch...
Bruno Mugat, Simon Nicot, Carolina Varela-Chavez, Christophe Jourdan, Kaoru Sato, Eugenia Basyuk, Fr...
2020 - Nature Communications volume
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Lysyl-tRNA synthetase produces diadenosine tetraphosphate to curb STING-dependent inflammation
J. Guerra, A.-L. Valadao, D. Vlachakis, K. Polak, I. K. Vila, C. Taffoni, T. Prabakaran, A. S. Marri...
2020 - Science Advances, 10.1126/sciadv.aax3333
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NF90 modulates processing of a subset of human pri-miRNAs
Grasso G, Higuchi T, Mac V, Barbier J, Helsmoortel M, Lorenzo C, Sanchez G, Bello M, Ritchie W, Saka...
2020 - Nucleic Acids Research
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4D Genome Rewiring during Oncogene-Induced and Replicative Senescence
Sati, S., Bonev, B., Szabo, Q., Jost, D., Bensadoun, P., Serra, F., Loubiere...
2020 - Mol Cell, 10.1016/j.molcel.2020.03.007
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The PIWI protein Aubergine recruits eIF3 to activate translation in the germ plasm.
Ramat A, Garcia-Silva MR, Jahan C, Naït-Saïdi R, Dufourt J, Garret C, Chartier A...
2020 - Cell Research (2020)., 10.1038/s41422-020-0294-9
Widespread activation of developmental gene expression characterized by PRC1-dependent chromatin loo...
Loubiere V, Papadopoulos GL, Szabo Q, Martinez AM, Cavalli G
2020 - Sci Adv, 6(2):eaax4001
31950077MRX Increases Chromatin Accessibility at Stalled Replication Forks to Promote Nascent DNA Resection ...
Delamarre A, Barthe A, de la Roche Saint-André C, Luciano P, Forey R, Padioleau I, Skrzypczak M, Gi...
2019 - Mol Cell, 77(2):395-410.e3
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MCM8- and MCM9 Deficiencies Cause Lifelong Increased Hematopoietic DNA Damage Driving p53- Dependent...
Malik Lutzmann, Florence Bernex, Cindy da Costa de Jesus, Dana Hodroj, Caroline Marty, Isabelle Plo,...
2019 - Cell Reports, 10.1016/j.celrep.2019.07.095
In utero exposure to acetaminophen and ibuprofen leads to intergenerational accelerated reproductive...
Rossitto M, Ollivier M, Déjardin S, Pruvost A, Brun C, Marchive C, Nguyen AL, Ghettas A, Keime C, d...
2019 - Communications Biology vol 2, 310 (2019)
Advances in epigenetics link genetics to the environment and disease
Giacomo Cavalli and Edith Heard
2019 - Nature, 10.1038/s41586-019-1411-0