Nucleic Acid Sensing by Innate Immune Receptors- A journey from MDA5 to cGAS

Jan is a Professor in the Medical Sciences Division at the University of Oxford. His  research focuses on the molecular biology of the activation and regulation of innate immune receptors that survey the cytosol, including the role of nucleic acid sensing in inflammatory diseases and in cancer. Jan is also interested in the molecular mechanisms underlying host-pathogen interactions. His work lies at the intersection of immunology, virology and molecular biology.