L'Institut de Génétique Humaine se mobilise pour apporter une réponse scientifique à COVID-19
en offrant son expertise et ses installations pour lutter contre la pandémie.
L'IGH a pour objectif de réaliser une recherche fondamentale d'excellence et de conduire celle-ci jusqu'à ses retombées dans le domaine de la pathologie.
Publications
Splicing-associated chromatin signatures: a combinatorial and position-dependent role for histone ma...
Agirre E, Oldfield AJ, Bellora N, Segelle A, Luco RF
2021 - Nat Commun, 12(1):682
33514745
TopBP1 assembles nuclear condensates to switch on ATR signaling.
Frattini C, Promonet A, Alghoul E, Vidal-Eychenie S, Lamarque M, Blanchard MP, Urbach S, Basbous J, ...
2021 - Mol Cell
33503405Plus d'informations
Htt is a repressor of Abl activity required for APP-induced axonal growth
Claire Marquilly,Germain U. Busto,Brittany S. Leger,Ana Boulanger,Edward Giniger,James A. Walker,Lee...
2021 - PLOS GENETICS
Plus d'informationsInteractions between gut microbiota and skeletal muscle.
Gizard F, Fernandez A, De Vadder F
2021 - Nutr Metab Insights, 13:1178638820980490
33402830Plus d'informations
A Role for the Mre11-Rad50-Xrs2 Complex in Gene Expression and Chromosome Organization
Romain Forey, Antoine Barthe, Mireille Tittel-Elmer, Maxime Wery, Marie-Bénédicte Barrault, Cécil...
2020 - Molecular cell
Plus d'informations
A predictable conserved DNA base composition signature defines human core DNA replication origins.
Akerman I, Kasaai B, Bazarova A, Sang PB, Peiffer I, Artufel M, Derelle R, Smith G, Rodriguez-Martin...
2020 - Nat Commun, 11(1):4826
32958757
Tubulin modifying enzymes as target for the treatment of tau-related diseases
Krzysztof Rogowski, Khaled Hached, Carole Crozet, Siem Van Der Laan
2020 - Pharmacology & Therapeutics
Plus d'informations
Functions of PIWI Proteins in Gene Regulation: New Arrows Added to the piRNA Quiver
Anne Ramat, Martine Simonelig
2020 - Trends in Genetics
The Mi-2 nucleosome remodeler and the Rpd3 histone deacetylase are involved in piRNA-guided heteroch...
Bruno Mugat, Simon Nicot, Carolina Varela-Chavez, Christophe Jourdan, Kaoru Sato, Eugenia Basyuk, Fr...
2020 - Nature Communications volume
Plus d'informations
Lysyl-tRNA synthetase produces diadenosine tetraphosphate to curb STING-dependent inflammation
J. Guerra, A.-L. Valadao, D. Vlachakis, K. Polak, I. K. Vila, C. Taffoni, T. Prabakaran, A. S. Marri...
2020 - Science Advances, 10.1126/sciadv.aax3333
Plus d'informations
NF90 modulates processing of a subset of human pri-miRNAs
Grasso G, Higuchi T, Mac V, Barbier J, Helsmoortel M, Lorenzo C, Sanchez G, Bello M, Ritchie W, Saka...
2020 - Nucleic Acids Research
Plus d'informations
4D Genome Rewiring during Oncogene-Induced and Replicative Senescence
Sati, S., Bonev, B., Szabo, Q., Jost, D., Bensadoun, P., Serra, F., Loubiere...
2020 - Mol Cell, 10.1016/j.molcel.2020.03.007
Plus d'informations