The Drosophila chemokine-like Orion bridges phosphatidylserine and Draper in phagocytosis of neurons
Hui Ji, Bei Wang, David Labib, Joyce Lei, Xinchen Chen, Maria Sapar, Ana Boulanger, Jean-Maurice Dura, Chun Han
Genetics, cell biology and development
Drosophila adult brain developmental molecular genetics is a youg science which is gaining momentum. We can raisonably foresee that the gene cascades at work during brain development will be conserved in mammals.
In Drosophila, recent techniques are now available and allow to work efficiently on this topic.
Mushroom bodies (MB) may be considered as the mamalian hippocampus analogue are an excellent model in order to study brain development. Each MB neuroblast generates, in a sequential fashion, three distinct classes of neurons.
First the γ then the α'β' and finally the αβ neurons appear during development.
MB are essential for several forms of learning and memory.
We have introduced in the laboratory a memory paradigm based on male courtship behavior (in collaboration with M.L. Parmentier and Y. Grau, IGF).
Therefore we are able to correlate a developing brain structure and its fonction.
Hui Ji, Bei Wang, David Labib, Joyce Lei, Xinchen Chen, Maria Sapar, Ana Boulanger, Jean-Maurice Dura, Chun Han
Ana Boulanger, Jean-Maurice Dura
Ana Boulanger, Camille Thinat, Stephan Züchner, Lee G. Fradkin, Hugues Lortat-Jacob & Jean-Maurice Dura
Claire Marquilly,Germain U. Busto,Brittany S. Leger,Ana Boulanger,Edward Giniger,James A. Walker,Lee G. Fradkin,Jean-Maurice Dura
Reynaud E, Lahaye LL, Boulanger A, Petrova IM, Marquilly C, Flandre A, Martianez T, Privat M, Noordermeer JN, Fradkin LG, Dura JM
Boulanger A, Dura JM.
Zirin J, Cheng D, Dhanyasi N, Cho J, Dura JM, Vijayraghavan K, Perrimon N.
Soldano A., Okray Z., Janovska P., Tmejova K., Reynaud E., Claeys A., Yan J., Atak Z. K., De Strooper B., Dura J.-M., Bryja V., Hasssan B. A.
Boulanger A, Farge M, Ramanoudjame C, Wharton K, Dura JM
Redt-Clouet C, Trannoy S, Boulanger A, Tokmatcheva E, Savvateeva-Popova E, Parmentier ML, Preat T, Dura JM
Trannoy S, Redt-Clouet C, Dura JM, Preat T.
Boulanger, A., Clouet-Redt, C., Farge, M., Flandre, A., Guignard, T., Fernando, C., Juge, F. & Dura, JM.
Fradkin, LG., Dura, JM., Noordermeer, JN
Grillenzoni, N., Flandre, A., Lasbleiz, C., Dura, JM
Taillebourg E., Moreau-Fauvarque C., Delaval K. and Dura J.-M.
Perrin L. and Dura J.-M.
Bloyer S, Cavalli G, Brock HW, Dura JM
Ringrose L., Rehmsmeier M., Dura J.-M. and Paro R.
Nicolaï M., Lasbleiz C. and Dura J.-M.
Perrin L., Bloyer S., Ferraz C., Agrawal N., Sinha P., and Dura J.-M.
Moreau-Fauvarque C., Taillebourg E., Préat T. and Dura J.-M.
Fauvarque M.-O., Laurenti P., Boivin A., Bloyer S., Griffin-Shea R., Bourbon H.-M. and Dura J.-M.
Taillebourg E. and Dura J.-M.
Taillebourg, E. and Dura, J.M.
Boivin, A., Fauvarque, M.O. and Dura, J.M.
Netter, S., Fauvarque, M.O., Diez del Corral, R., Dura, J.M. and Coen, D.
Moreau, C., Taillebourg, E., Boissoneau, E., Mesnard, J. and Dura, J.M.
Boivin, A. and Dura, J.M.
Defended by Claire Marquilly on 25-09-2017