News

The "3D Organization of our Genome” video

Chromatin and cell biology

A video illustrating the organization of the genome in 3D has been released by the Cavalli team. The video summarizes the current understanding of genome organization in the three-dimensional space of the cell nucleus. It illustrates the different layers of chromosome organization, from nucleosomes, which envelop 146 base pairs of DNA, to chromosome territories, which can contain hundreds of millions of base pairs of DNA sequence. Between these two extremes, the hierarchical folding of the chromatin fiber into "nucleosome clusters", "chromatin nanodomains or CNDs", "Topologically Associating Domains or TADs" (including their formation mechanism via loop-extrusion) and "Compartments A and B" are presented.
In the description of the video, references can be found that complete the content.

Team website page >>

Thanks to :
Fred Bantignies, IGH, CNRS et Univ. de Montpellier, France
Quentin Szabo, Dept Mol Life Sciences, University of Zürich, Suisse
and also :
Arkitek Scientific

New challenges in HIV research

Forty years after its discovery, HIV/AIDS has become a chronic disease thanks to triple therapy. But it still resists being cured and the vaccine is still awaited...


Monsef Benkirane, virologist at the Institute of Human Genetics, takes stock of the new research challenges.


Read the full interview

Axel Kahn "being human"

In tribute to Axel Kahn who passed away on 6 July 2021, the IGH looks back on a rich day during which Axel Kahn honoured us with his presence.

On April 15, 2016 Axel Kahn spoke at the Genopolys amphitheatre as part of the Citizens' Days. The conference inaugurated the EUREKA cycle, with a reflection on the human being, this animal endowed with reason.

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Open Group Leader Position

The Institute of Human Genetics of Montpellier (IGH) opens a call for applications to a Principal Investigator position in its main areas of interest, namely Genome Dynamics, Genomics, RNA Biology, Computational Biology and AI, Epigenetics, Immunogenetics, Developmental Biology, Cancer and Infectious Diseases.

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Nature publication by the LifeTime Initiative: Improving Healthcare and Healthcare Systems in Europe Through "Interceptive" Cellular Medicine

The LifeTime initiative, in which the Institute of Human Genetics (IGH), the CNRS and the Institut Curie participate, brings together hundreds of researchers, clinicians, industry leaders and policy makers both in France and in Europe. Together, they publish their LifeTime Strategic Research Agenda as well as an article in Nature on September 7, 2020, providing their vision and a roadmap for the coming decade.

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IGH's scientific response to COVID-19

During the developing COVID-19 pandemic the Institute of Human Genetics and its researchers are playing their part in tackling the virus.

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L'Institut de Génétique Humaine fête ses 20 ans

Pour célébrer cet anniversaire, l'IGH, en partenariat avec la nouvelle Faculté de Médecine de Montpellier, accueille un panel prestigieux de scientifiques internationaux pour une série de conférences.

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Résultats du premier appel à projet recherche de l'I-Site MUSE

Machine learning and gene regulation

This Wednesday, December 20, 2017, the MUSE board met to define and announce the final list of winning projects to the call for Research Support projects. 58 projects were selected out of 260 applications submitted, including the one led by William Richie from the Artificial Intelligence and Gene Regulation team at L'IGH.