Publications
The BLM helicase is a new therapeutic target in multiple myeloma involved in replication stress survival and drug resistance.
Epigenome modifications and genomic instability in normal and malignant B cells+ Genetic Instability and Cancer / Maintenance of genome integrity during DNA replication
Ovejero S, Viziteu E, Dutrieux L, Devin J, Lin YL, Alaterre E, Jourdan M, Basbous J, Requirand G, Robert N, de Boussac H, Seckinger A, Hose D, Vincent L, Herbaux C, Constantinou A, Pasero P, Moreaux J
Replication gap suppression depends on the double-strand DNA binding activity of BRCA2
Genetic Instability and CancerDomagoj Vugic, Isaac Dumoulin, Charlotte Martin, Anna Minello, Lucia Alvaro-Aranda, Jesus Gomez-Escudero , Rady Chaaban , Rana Lebdy , Catharina von Nicolai , Virginie Boucherit , Cyril Ribeyre , Angelos Constantinou, Aura Carreira
LAIR1, an ITIM-Containing Receptor Involved in Immune Disorders and in Hematological Neoplasms.
Epigenome modifications and genomic instability in normal and malignant B cellsVan Laethem F, Donaty L, Tchernonog E, Lacheretz-Szablewski V, Russello J, Buthiau D, Almeras M, Moreaux J, Bret C
Chromatin-associated YTHDC1 coordinates heat-induced reprogramming of gene expression
Gene regulationKalina Timcheva, Solenne Dufour, Leila Touat-Todeschini, Callum Burnard, Marie-Christine Carpentier, Florent Chuffart, Rémy Merret, Marion Helsmoortel, Sabrina Ferré, Aude Grézy, Yohann Couté, Sophie Rousseau, Saadi Khochbin, Claire Vourc’h, Cécile Bousquet-Antonelli, Rosemary Kiernan, Daphné Seigneurin-Berny and André Verdel
Programmed DNA elimination: New metazoan models.
Epigenetic Chromatin RegulationMochizuki K
TOPOVIBL-REC114 interaction regulates meiotic DNA double-strand breaks
Meiosis and recombinationNore, A. Juarez-Martinez, A. B. Clement, J. Brun, C. Diagouraga, B. Laroussi, H. Grey, C. Bourbon, H. M. Kadlec, J. Robert, T. de Massy, B.
The Polyvalent Role of NF90 in RNA Biology
Gene regulationGiuseppa Grasso and Rosemary Kiernan
Targeting the β(2) -adrenergic receptor increases chemosensitivity in multiple myeloma by induction of apoptosis and modulating cancer cell metabolism.
Epigenome modifications and genomic instability in normal and malignant B cellsSatilmis H, Verheye E, Vlummens P, Oudaert I, Vandewalle N, Fan R, Knight JM, De Beule N, Ates G, Massie A, Moreaux J, Maes A, De Bruyne E, Vanderkerken K, Menu E, Sloan EK, De Veirman K
Evolution and Diversity of the TopoVI and TopoVI-like Subunits With Extensive Divergence of the TOPOVIBL subunit
Meiosis and recombinationBrinkmeier, J. Coelho, S. de Massy, B. Bourbon, H. M.

Repression and 3D-restructuring resolves regulatory conflicts in evolutionarily rearranged genomes.
Chromatin and cell biologyRingel AR, Szabo Q, Chiariello AM, Chudzik K, Schöpflin R, Rothe P, Mattei AL, Zehnder T, Harnett D, Laupert V, Bianco S, Hetzel S, Glaser J, Phan MHQ, Schindler M, Ibrahim DM, Paliou C, Esposito A, Prada-Medina CA, Haas SA, Giere P, Vingron M, Wittler L, Meissner A, Nicodemi M, Cavalli G, Bantignies F, Mundlos S, Robson MI
Regulation of innate immunity by Nrf2
Molecular Basis of Inflammationvan der Horst D, Carter-Timofte ME, van Grevenynghe J, Laguette N, Dinkova-Kostova AT, Olagnier D
Emerging roles and functional mechanisms of PIWI-interacting RNAs.
mRNA Regulation and DevelopmentWang X, Ramat A, Simonelig M, Liu MF

NF90 interacts with components of RISC and modulates association of Ago2 with mRNA.
Gene regulationGrasso G*, Akkawi C*, Franckhauser C, Nait-Saidi R, Bello M, Barbier J, Kiernan R

Alternative pathways driven by STING: From innate Immunity to lipid metabolism.
Molecular Basis of InflammationVila IK, Guha S, Kalucka J, Olagnier D, Laguette N.
Integrative Analysis Reveals Histone Demethylase LSD1 Promotes RNA Polymerase II Pausing
Biology of distal regulatory elementsKim HJ, Li P, Kim T, Oldfield AJ, Zheng X, Yang P.
Activating translation with phase separation
mRNA Regulation and DevelopmentAnne Ramat and Martine Simonelig
Coupling crossover and synaptonemal complex in meiosis
Meiosis and recombinationCorinne Grey and Bernard de Massy