Protocol to induce and assess cGAS-STING pathway activation in vitro.

Molecular Basis of Inflammation

Chamma H, Guha S, Laguette N, Vila IK

Activation of STING in the pancreatic tumor microenvironment: A novel therapeutic opportunity

Molecular Basis of Inflammation

Hanane Chamma, Isabelle K Vila, Clara Taffoni, Andrei Turtoi, Nadine Laguette

A shared ancient enhancer element differentially regulates the bric-a-brac tandem gene duplicates in the developing Drosophila leg.

Chromatin and cell biology

Bourbon HG, Benetah MH, Guillou E, Mojica-Vazquez LH, Baanannou A, Bernat-Fabre S, Loubiere V, Bantignies F, Cavalli G, Boube M

TRIM28-dependent SUMOylation protects the adult ovary from the testicular pathway

Development and Pathology of the gonad

Moïra Rossitto , Stephanie Déjardin , Chris M Rands , Stephanie Le Gras , Roberta Migale , Mahmoud-Reza Rafiee , Yasmine Neirijnck , Alain Pruvost , Anvi Laetitia Nguyen , Guillaume Bossis , Florence Cammas , Lionel Le Gallic , Dagmar Wilhelm , Robin Lovell-Badge , Brigitte Boizet-Bonhoure , Serge Nef , Francis Poulat

Using Experimental Models to Decipher the Effects of Acetaminophen and NSAIDs on Reproductive Development and Health

Development and Pathology of the gonad

B. Boizet-Bonhoure, S. Dejardin, M. Rossitto, F. Poulat and P. Philibert

Comprehensive characterization of the epigenetic landscape in Multiple Myeloma.

Chromatin and cell biology

Alaterre E, Ovejero S, Herviou L, de Boussac H, Papadopoulos G, Kulis M, Boireau S, Robert N, Requirand G, Bruyer A, Cartron G, Vincent L, Martinez AM, Martin-Subero JI, Cavalli G, Moreaux J

HiCmapTools: a tool to access HiC contact maps.

Chromatin and cell biology

Chang JM, Weng YF, Chang WT, Lin FA, Cavalli G

SETDB1/NSD-dependent H3K9me3/H3K36me3 dual heterochromatin maintains gene expression profiles by bookmarking poised enhancers.

Chromatin and cell biology

Barral A, Pozo G, Ducrot L, Papadopoulos GL, Sauzet S, Oldfield AJ, Cavalli G, Déjardin J

Mechanisms of Polycomb group protein function in cancer.

Chromatin and cell biology

Parreno V, Martinez AM, Cavalli G

Activation of the ubiquitin-proteasome system contributes to oculopharyngeal muscular dystrophy through muscle atrophy.

mRNA Regulation and Development

Ribot C, Soler C, Chartier A, Al Hayek S, Naït-Saîdi R, Barbezier N, Coux O, Simonelig M

Molecular mechanisms of transgenerational epigenetic inheritance.

Chromatin and cell biology

Fitz-James MH, Cavalli G

STING orchestrates the crosstalk between polyunsaturated fatty acid metabolism and inflammatory responses

Molecular Basis of Inflammation

Isabelle K.Vila, Hanane Chamma, Alizée Steer, Mathilde Saccas, Clara Taffoni, Evgenia Turtoi, Line S.Reinert, Saqib Hussain, Johanna Marines, Lei Jin, Xavier Bonnefont, Mathieu Hubert, Olivier Schwartz, Soren R.Paludan, Gaetan Van Simaeys, Gilles Doumont, Bijan Sobhian, Dimitrios Vlachakis, Andrei Turtoi, Nadine Laguette


Studying the DNA damage response in embryonic systems.

Genome Surveillance and Stability

Lo Furno E, Recolin B, van der Laan S, Aze A, Maiorano D