Our research interest is to understand how human cells deal with genotoxic stress assaults and how they coordinate genome maintenance mechanisms with other vital cellular functions. To this end we combine state-of-the-art molecular biology and biochemistry with powerful advanced cell imaging technologies, in particular employing single cell chromatin perturbations, high resolution live cell imaging, automated quantitative microscopy and software-assisted image analysis. By targeted ablation of specific gene functions and high content analyses of DNA damage and repair markers we aim at identifying concealed regulators of the cellular response network to genotoxic stress and at understanding their role for genome maintenance.
Dynamics and Functions of DNA Repair Compartments
ORGANISÉ PAR L'IGH
International Summer-School on Epigenetics du 15/07/2024 jusqu'au 19/07/2024 Genopolys, Montpellier - France
Méiose et recombinaisonMBHD Dpt. Seminar Series
IGH Seminar Series of the Department “Molecular basis of Human Diseases” du 02/04/2024 jusqu'au 11/10/2024 11:30 - 14:00 Genopolys amphitheater
GCB&D Dpt. Seminar Series
IGH Seminar Series of the Department “Genetics, Cell Biology and Development” du 19/02/2024 jusqu'au 15/11/2024 Genopolys amphitheater
Séminaires
The nuclear pore complex in ageing - A landmark structure at the crossroads of genome stability and protein homeostasis.
Architecture nucléaire dans les contextes physiologiques et pathologiques 24/05/2024 11:30 Genopolys AmphitheatreDNA Replication Forks and the DNA Damage Checkpoint
Réplication et Dynamique du Génome 04/06/2024 11:30 Genopolys AmphitheatreDecoding the transcription circuitry in early mammalian development
Méiose et recombinaison 11/07/2024 11:30 Genopolys AmphitheatreCongrès
International Summer-School on Epigenetics
Méiose et recombinaison 15/07/2024 jusqu'au 19/07/2024 Genopolys, Montpellier - FranceTranscription and Genome maintenance
09/09/2024 jusqu'au 13/09/2024 Roscoff, France2024 RNase H meeting
16/09/2024 jusqu'au 18/09/2024 Engelthal Ingelheim, GermanyZoom
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