History, achievements, promises, and issues of Gene therapy
Presented by Serge Braun, Scientific Director of l’AFM-Téléthon
Institute Life > Séminars
Séminars
Genome and epigenome replication in mammalian cells
Formation and function of 3D chromatin domains in gene regulation
Dissecting Enhancer and Promoter Dynamics in Transcription
Nuclear architecture- Cause and consequences on genome functions
Enhancer RNAs stimulate Pol II pause release by harnessing multivalent interactions to NELF
mRNA Regulation and DevelopmentZoom link: https://umontpellier-fr.zoom.us/j/87674664494?pwd=NVBwNk5xQkRxQ2ZjWmd5bDdLQjB0UT09
ID de réunion: 876 7466 4494; Code secret: 446615
Molecular clock mechanisms that control skin regeneration
Systemic impact of small regulatory RNAsZoom link: https://umontpellier-fr.zoom.us/j/87674664494?pwd=NVBwNk5xQkRxQ2ZjWmd5bDdLQjB0UT09
ID de réunion: 876 7466 4494; Code secret: 446615
Chromatin network approaches to explore the epigenomic bases of heterogeneity and plasticity
There is strong evidence for a relationship between the topological properties of chromatin contacts and cellular phenotype.
https://umontpellier-fr.zoom.us/j/88189136799?pwd=SmVCSGozVWtXWTAxNkZyYWNkSGttUT09
Meeting ID: 881 8913 6799
Passcode: Pancaldi
Chromosome Doomsday
Chromatin and cell biologyWorkshop on “Chromosome Doomsday” discussing modelling approaches to understand Principles of 3D Genome Regulation, with two invited distinguished speakers:
Mario Nicodemi,
> Professor of Theoretical Physics and mathematical modelling at the Università di Napoli “Federico II”.
> Einstein BIH Visiting Professor at the MDC in Berlin
Talk at 10:30 AM - Talk title: “Polymer phase separation controls chromatin architecture in single-cells”
Leonid Mirny,
> Professor of Health Sciences & Technology, and Physics, MIT
> Blaise Pascal Chair of Excellence
Talk at 11:30 AM - Talk title "The interplay of physical mechanisms in chromosome organization”
https://umontpellier-fr.zoom.us/j/89872383476?pwd=OVZ1UGNkY0hPYVc3SUtaSmdQYTM4QT09
Meeting ID: 898 7238 3476
Passcode: 890328
Genome diversity and instability in the human germline
Meiosis and recombinationBio sketch:
Eva Hoffmann is professor in genomics and reproductive health at the Medical School, University of Copenhagen, Denmark. Her lab investigates genome diversification processes in the human germline using single-cell and low-input genomics, in particular meiotic recombination and chromosome segregation. They also assess the impact on the high rate of chromosome errors on fertility and congenital disorders (Gruhn et al, Science, 2019). Eva serves on the executive board of ReproUnion (www.reprounion.eu) and is their Scientific Coordinator. Research in her lab is funded by the European Research Council and the Novo Nordisk Foundation.