Institute Life > Séminars


History, achievements, promises, and issues of Gene therapy

 Presented by Serge Braun, Scientific Director of  l’AFM-Téléthon

Genome and epigenome replication in mammalian cells

Formation and function of 3D chromatin domains in gene regulation

Dissecting Enhancer and Promoter Dynamics in Transcription

Nuclear architecture- Cause and consequences on genome functions

Chromosome Doomsday

Chromatin and cell biology

Workshop on  “Chromosome Doomsday” discussing modelling approaches to understand Principles of 3D Genome Regulation, with two invited distinguished speakers:

Mario Nicodemi

> Professor of Theoretical Physics and mathematical modelling at the Università di Napoli “Federico II”.

> Einstein BIH Visiting Professor at the MDC in Berlin  

Talk at 10:30 AM - Talk title: “Polymer phase separation controls chromatin architecture in single-cells”

Leonid Mirny

> Professor of Health Sciences & Technology, and Physics, MIT

> Blaise Pascal Chair of Excellence

Talk at 11:30 AM - Talk title "The interplay of physical mechanisms in chromosome organization”
Meeting ID: 898 7238 3476
Passcode: 890328

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Genome diversity and instability in the human germline

Meiosis and recombination

Bio sketch:

Eva Hoffmann is professor in genomics and reproductive health at the Medical School, University of Copenhagen, Denmark. Her lab investigates genome diversification processes in the human germline using single-cell and low-input genomics, in particular meiotic recombination and chromosome segregation. They also assess the impact on the high rate of chromosome errors on fertility and congenital disorders (Gruhn et al, Science, 2019). Eva serves on the executive board of ReproUnion ( and is their Scientific Coordinator. Research in her lab is funded by the European Research Council and the Novo Nordisk Foundation.

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