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Séminars

Speaker: Dr. Marlene Oeffinger (Institut de recherches cliniques de Montréal)
Seminar room of Genopolys

Heterogeneity of RNA machines

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Contact IGH Edouard BERTRAND

Speaker: Dr. Daniel Zenklusen (Département de biochimie et médicine moléculaire, Université de Montréal)
Seminar room of Genopolys

Investigating spatio-temporal dynamics of RNA metabolism, one molecule at the time

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Contact IGH Edouard BERTRAND

Speaker: Anne-Kathrin Classen (University of Freiburg, Germany)
Amphitheatre Génopolys

Spatio-temporal organization of tissue repair and regeneration

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Contact IGH Giacomo CAVALLI

Speaker: Axel Delamarre
Amphitheater of genopolys

Proximity Copy Paste (PCP) : A new method to map the 3D organization of chromatin
Proximity Copy Paste (PCP): A new method to map the 3D organization of chromatin Understanding the principles of three-dimensional genome organization is essential to comprehend genome maintenance, expression, and duplication. Current Hi-C based methods use fragmentation of crosslinked chromatin followed by proximity ligation to detect DNA molecules whose extremities can be ligated together. While powerful, these approaches are limited because only ligatable, pairwise interactions are mapped,...

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Contact IGH Armelle LENGRONNE

Maintenance of genome integrity during DNA replication

Speaker: Shan Gao (Ocean University of China)
Genopolys Amphitheater

de novo methylation of N6-methyladenine (6mA) showcased in the unicellular eukaryote Tetrahymena
DNA N6-adenine methylation (6mA) is rediscovered as an important epigenetic mark in eukaryotes. It however remains unclear what the de novo methyltransferases (MTases) are and how they fulfill their biological functions. The binucleated Tetrahymena thermophila happens to possess a unique time window for the study of de novo methylation, when the 6mA-free zygotic nucleus develops into 6mA-positive new macronucleus (MAC). In this study, we found that the MT-A70 family members, AMT2 and AMT5, are not...

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Contact IGH Kazufumi MOCHIZUKI

Epigenetic Chromatin Regulation

Speaker: Ashley Albright (University of California, San Francisco - Wallace Marshall lab)
Genopolys Amphitheater

Patterning and gene expression in established and emerging model systems
The regulation of gene expression is crucial for all living organisms. Much of our understanding of the regulation of gene expression comes from early embryonic development in Drosophila melanogaster. However, understanding the regulation of gene expression is challenging due to the need to capture expression levels and patterning information simultaneously. Upon conducting single-nucleus RNA-sequencing in maternal null dCTCF, an insulator protein, embryos we found that early embryonic nuclei can...

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Contact IGH Kazufumi MOCHIZUKI

Speaker: Kateryna Makova
Genopolys

Telomere-to-telomere assemblies uncover secrets of ape sex chromosomes
Evolution of ape sex chromosomes has remained enigmatic due to their highly repetitive nature and incomplete reference assemblies (particularly for the Y). Here we generated gapless, telomere-to-telomere assemblies of the X and Y chromosomes for all extant great ape species—chimpanzee, bonobo, gorilla, Bornean and Sumatran orangutans—and for an outgroup lesser ape, the siamang. To achieve this, we utilized state-of-the-art experimental and computational methods developed for deciphering the human...

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Contact IGH Philippe PASERO

Maintenance of genome integrity during DNA replication

Speaker: Yukiko Imai (National Institute of Genetics, Mishima, Japan)
IGH Seminar room 1st floor

Initiation of meiotic recombination in zebrafish

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Contact IGH Bernard DE MASSY

Meiosis and recombination

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